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Trends: A Brief introduction to microRNA
Why study microRNA?
MicroRNAs are important regulators in post-transcriptional gene regulation. The active secretion of miRNA into circulation during diseases onset renders it a promising biomarker candidate.
In the last 10 years, a growing number of studies and reviews have associated presence of various miRNAs with progression of cancer. miRNA expression fingerprints had been shown to correlate with clinical and biological characteristics of tumors, including tissue type, differentiation, aggression and response to therapy. There have been ~12000 in the last 9 years and virtually every publication involves quantification of microRNA.
Prelude: microRNA
Presenting to you - eleven pathways, which MiRXES had co-developed with Clarivate Analytics – market leader in pharmaceutical and biotechnology intelligence. All 352 highly curated and wet-lab validated miRNA are from MiRXES ID3EAL Cancer microRNA Knowledge panel and are strongly associated with various cancer types and known to regulate up to hundreds of key onco- and tumour suppressor genes and pathways.
Reference Guide
co-developed with Clarivate Analytics
derived from MiRXES Knowledge Panel
microRNA
Pathway
11 vital pathways involved in Oncology
Mapped out using 352 highly curated miRNA
MiRXES ID3EAL miRNA qPCR Starter kit is also available
learn more about MiRXES ID3EAL miRNA qPCR Starter kit
pathways
miRNA Assays
MiRXES redefines miRNA Quantification
Get the best-in-class
performance
MiRXES miRNA solutions had found its way to bring you unparalleled specificity. MiRXES assays are based on an unique 3-specific priming strategy, and no random priming is involved. These assays are also designed using in-house proprietary algorithm to boosted its sensitivity. All assays have been wet-lab validated, in accordance to MiQE guidelines and when presented together, all these factors sets MiRXES apart from assays available in the market.
It is a known challenge that the quantification of microRNA are extremely small and shares high homology, hence hampering accurate quantification.
Watch: MiRXES patented technology
using 3-specific priming strategy
For initial starters to microRNA research, MiRXES ID3EAL miRNA qPCR Starter kit is also available. The starter kit is an all-inclusive kit that consists of reagents required to perform 20 cDNA reactions, 100qPCR reactions, and two validated primer sets of choice*.
miRNA Starter kit
product info here
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